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Lyme disease (Borreliosis)

General Information

No vaccine against Borreliosis is currently available, so tick awareness, appropriate clothing in tick-infested areas, and early removal of attached ticks remain the most important prevention measures.​

Transmission

Lyme disease is caused by the bacterium Borrelia burgdorferi and is transmitted to humans by the bite of infected ticks.

Symptoms

Typical symptoms include fever, headache, fatigue, and a characteristic skin rash called erythema migraines.

If left untreated, infection can spread to joints, the heart, and the nervous system. Most cases of Lyme disease can be treated successfully with a few weeks of antibiotics.

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Epidemiology

≈476,000 cases are diagnosed and treated per year in the United States and >200,000 cases per year in western Europe.​

Vaccines
Pipeline

1
Vaccines in
the pipeline

Technology Platforms

  • Protein subunit​ (1)

DEVELOPMENT PHASES

  • Phase III (1)

TRIAL POPULATION

    Paediatric + Adults (1)​

Source: 
https://www.ecdc.europa.eu/en/borreliosis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314816/
[Accessed: November 2022]

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