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Shigellosis

General Information

Shigellosis is a gastrointestinal infection caused by one of four species of Shigella.

Symptoms

Most people with Shigella infection have diarrhea (sometimes bloody), fever, and stomach cramps. Symptoms usually begin 1–2 days after infection and last 7 days. Most people recover without needing antibiotics. However, people with severe illness and those with underlying conditions that weaken the immune system should be given antibiotics.

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Epidemiology

2017

In Europe, 30 EU/EEA countries reported 6,337 confirmed shigellosis cases in 2017.

An estimated 77,000 antibiotic resistant Shigella infections occur in the United States each year.

Vaccines
Pipeline

1
Vaccines in
the pipeline

Technology Platforms

  • Glycoconjugate vaccine (1)

DEVELOPMENT PHASES

  • Phase II (1)

TRIAL POPULATION

    Paediatric + Adults (1)​

Sources: 
https://www.ecdc.europa.eu/en/shigellosis/facts
https://www.cdc.gov/shigella/index.html
[Accessed: November 2022]

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