450,000 infections in the United States each year and an estimated $93 million in direct medical costs. Of these, 77,000 infections are antibiotic resistant.
Shigellosis is a gastrointestinal infection caused by one of four species of Shigella.
Shigella was found to be one of the top four attributable pathogens overall in children younger than 5 years of age with moderate to severe diarrhea.
Symptoms of Shigella infection vary from mild, watery diarrhea to severe abdominal pain, and blood and mucus in the stools.
Shigella bacteria cause disease by invading the human lower intestine (colon) and causing intense inflammation and epithelial destruction.
Symptoms usually begin 1–2 days after infection and last 7 days. Most people recover without needing antibiotics. However, people with severe illness and those with underlying conditions that weaken the immune system should be given antibiotics.
450,000 infections in the United States each year and an estimated $93 million in direct medical costs. Of these, 77,000 infections are antibiotic resistant.
In the EU/EEA, 8,400 confirmed cased of shigellosis have been reported in 2019.
Generalised Modules for Membrane Antigens (1)