Noroviruses are highly contagious and 10-100 viral particles may be sufficient to infect an individual. They can cause gastrointestinal illnesses to humans.
Norovirus
General Information
Transmission
They are transmitted primarily through the faecal-oral route, either by consumption of contaminated food or water, or by spreading directly from person to person.
Symptoms
Infection with norovirus can cause vomiting, diarrhoea, and stomach pain, resulting in fluid loss.
As immunity may only last a few months and is strain-specific, and given their genetic variability, infection can happen several times in a lifetime and affects individuals of all ages.
Epidemiology
Norovirus causes approximately 685 million cases annually. Of those, around 200 million cases are seen among children under 5 years old, leading to an estimated 50,000 child deaths every year.
Vaccines Pipeline
2
Vaccines in
the pipeline
the pipeline
TECHNOLOGY PLATFORMS
mRNA (2)
DEVELOPMENT PHASES
Phase I (1)
Phase II (2)
TRIAL POPULATION
Adults + Older Adults (2)
Source:
ECDC. Facts about norovirus. 2017. Available from: https://www.ecdc.europa.eu/en/norovirus-infection/facts.
Norovirus burden and trends. 2024. Available from: https://www.cdc.gov/norovirus/about/index.html
[Accessed: August 2024]