Malaria is a life-threatening disease caused by Plasmodium parasites that is preventable and curable.
The WHO African Region carries a disproportionately high share of the global malaria burden. In 2022, the region was home to 94% of malaria cases and 95% of malaria deaths. Children under 5 accounted for about 80% of all malaria deaths in the Region.
Since October 2021, WHO recommends broad use of the RTS,S/AS01 malaria vaccine among children living in regions with moderate to high malaria transmission. The vaccine has been shown to significantly reduce malaria, and deadly severe malaria among young children.
A second malaria vaccine (R21) has been recommended by WHO in December 2023.