𝘚𝘡𝘒𝘱𝘩𝘺𝘭𝘰𝘀𝘰𝘀𝘀𝘢𝘴 𝘒𝘢𝘳𝘦𝘢𝘴 infection

General Information

Staphylococcus aureus asymptomatically colonises about 21–30% of people. It remains a leading cause of both superficial and invasive infections, including pneumonia, bacteraemia, endocarditis, osteomyelitis, toxic shock syndrome, and sepsis.

Some types of Staphylococcus aureus are resistant to antibiotics.

Transmission

People with chronic health conditions have a higher risk of S. aureus infections. In hospital settings, the risk of more serious S. aureus infection is higher for patients.

Symptoms

Most of the time, S. aureus doesn’t cause any harm, but it can sometimes cause infections. S. aureus infections can look like pimples, boils or other skin conditions.

Epidemiology

2021

In 2019, Methicillin-resistant aureus (MRSA) was linked to approximately 100,000 deaths globally due to AMR, and attributable MRSA deaths have more than doubled since 1990, reaching around 130,000 by 2021.

Vaccines Pipeline

1
Vaccines in
the pipeline

IMMUNISATION TECHNOLOGY

Monoclonal antibody (1)

DEVELOPMENT PHASES

Phase II (1)

TRIAL POPULATION

Adults (1)

Source:
Touaitia R, Mairi A, Ibrahim NA, Basher NS, Idres T, Touati A. Staphylococcus aureus: A Review of the Pathogenesis and Virulence Mechanisms. Antibiotics. 2025; 14(5):470.
Navidifar Tahereh, Zare Banadkouki Abbas, Parvizi Elnaz, Mofid Maryam, Golab Narges, Beig Masoumeh, Sholeh Mohammad. Global prevalence of macrolide-resistant Staphylococcus spp.: a comprehensive systematic review and meta-analysis. JOURNAL Frontiers in Microbiology. VOLUME=Volume 16 – 2025. 2025.
CDC. https://www.cdc.gov/staphylococcus-aureus/about/index.html
[Accessed: August 2025]